Semax vs Selank
Semax is an ACTH (4–10) analogue studied for cognition, attention and neuroprotection through BDNF; selank is a tuftsin analogue studied for anxiety through GABA and enkephalin systems. Both come from the same Moscow institute, share the Pro-Gly-Pro tail, and are used as nasal products in Russia. Peptide Aus supplies both as 10mg vials for research.
Origin and structure
Both were developed at the Institute of Molecular Genetics in Moscow. Semax is Met-Glu-His-Phe-Pro-Gly-Pro, from the ACTH fragment; selank is Thr-Lys-Pro-Arg-Pro-Gly-Pro, from the immune peptide tuftsin.
Mechanism and research focus
Semax raises BDNF and TrkB expression and modulates monoamines; its studies cover stroke recovery, attention and neuroprotection. Selank modulates GABA-A expression and inhibits enkephalin breakdown; its studies cover anxiety without sedation.
What the studies report
Semax: improved outcomes in Russian stroke trials and improved attention scores; rodent learning gains. Selank: anxiolytic effects comparable to medazepam in a Russian trial, without dependence or sedation. Neither has Western controlled trials.
Nasal sprays
Both are registered nasal products in Russia, which is why 'semax nasal spray' outsearches the compound in many markets. Sprays sold online elsewhere carry no verified content. The research vial is the verifiable format.
Using both
Research designs sometimes run them together because the targets differ: cognition versus anxiety. There is no published interaction data.
Frequently asked questions
Is N-acetyl semax better?
Modified forms are marketed as longer-acting; the published research is on the original sequences.
Are they legal in Australia?
Neither is registered in Australia. Research supply is for laboratory use only.
Kits
Nootropic Pair (Semax + Selank)
Semax and Selank 10mg vials with water, forty syringes and swabs.
Nootropic Pair (Semax + Selank)
Semax and Selank 10mg vials with water, forty syringes and swabs.
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